I'm not sure I'd read too much into Nylander and Hyman being on opposite wings. Sometimes it's just a typo or one-off thing.
This sets up Mikheyev-Tavares-Marner to be the other big line, and probably Clifford-Gauthier-Spezza as the 4th line.
Also probably means Muzzin-Holl is the shutdown pairing and Dermott-Barrie is the offensive/sheltered pairing.