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Unless the coach is dropping Matthews, or Marner, or Tavares, or Nylander, or Rielly, or Giordano, or Brodie, or Campbell from the lineup for non-health related reasons, there isn't really much to fret about.
The opening night roster is never the game 82 roster, and the playoffs is no different outside the core players. Liljegren will get some rest and some perspective in the box. Holl and Spezza are coming in with fresh legs and a bit of a chip on the shoulder to prove they should be fixtures. Give the opponents something different to adjust to.